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Nottingham Arabidopsis Stock Centre

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Nottingham Arabidopsis Stock Centre
Websitehttp://www.arabidopsis.info

The Nottingham Arabidopsis Stock Centre (NASC) provides seed and information resources to the International Arabidopsis Genome Project and the wider research community. It is based in the School of Biosciences at the University of Nottingham's Sutton Bonington Campus, in the English county of Nottinghamshire.

It holds more than 800,000 different stocks of seed representing nearly a million genotypes and provided a Genechip service from 2002-2013. Newly generated research stocks, mutants or lines of Arabidopsis thaliana are donated as samples to NASC where they are maintained and thus are made available to scientists worldwide.

Main regeneration glasshouses at NASC holding ~10,000 stocks in each cycle.
Main regeneration glasshouses at NASC holding ~10,000 stocks in each cycle.
Photographs of example arabidopsis ecotypes (left) and a mutant line (right) taken within NASC from real stocks available to the scientific public.
Photographs of example arabidopsis ecotypes (left) and a mutant line (right) taken within NASC from real stocks available to the scientific public.

Established in 1990 [1][2] as part of the Plant Molecular Biology initiative of the Agricultural and Food Research Council (AFRC), the Centre is currently funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the University of Nottingham.

The Stock Centre was founded by Dr Bernard Mulligan; Directed from 1991 to 1999 by Dr Mary Anderson and from 1999–present by Prof. Sean Tobias May.

NASC's activities are coordinated with those of the Arabidopsis Biological Resource Center, (ABRC) based at Ohio State University, USA. This facilitates a unified and efficient service for the research community.

The stock centres have a distribution agreement. NASC distributes to Europe and ABRC distributes to the Americas. Laboratories in other locations may establish their primary affiliation with either centre.

When NASC started in 1990 it inherited hundreds of stocks from the Arabidopsis Information Service (AIS) - Started by Robbelen in 1965 and continued by Burger (1971), Kranz (1978), and Kranz and Kirchheim (1981, 1987), the AIS donated its complement of stocks listed in the 24th edition of the AIS stock book.[3] Stock numbers held at NASC/ABRC in the 1990s then increased steadily by many hundreds mainly due to new technologies of mass transformation (e.g. seed transformation by Ken Feldmann, University of Arizona); but also due to many new mutagenesis programs encouraged by the development of Arabidopsis as a major model organism accompanied by generous donations of seed from many international members of the community.

In 1999 NASC received a large influx of thousands of stocks generated through T-DNA transformation and donated by Pelletier and Bechtold from INRA. This was the first of many very large populations that came out of the community and which took the complement of stocks held by the stock centres into the hundreds of thousands. The largest (most populous) seed donations have been the GABI-kat lines from Germany via Bernd Weisshaar;[4] and the SALK lines from Joe Ecker.[5] Between them, these two populations account for more than half of all stocks held by the stock centres today.

Discover more about Nottingham Arabidopsis Stock Centre related topics

University of Nottingham

University of Nottingham

The University of Nottingham is a public research university in Nottingham, United Kingdom. It was founded as University College Nottingham in 1881, and was granted a royal charter in 1948. The University of Nottingham belongs to the research intensive Russell Group association.

Nottinghamshire

Nottinghamshire

Nottinghamshire is a ceremonial and non-metropolitan county in the East Midlands, England. A landlocked county, it is bordered by South Yorkshire to the north-west, Lincolnshire to the east, Leicestershire to the south, and Derbyshire to the west. The most-populated settlement is the City of Nottingham, which is administered as a unitary authority area. Nottinghamshire County Council, which administers the rest of the county, is based at West Bridgford in Rushcliffe. In 2017, the population was estimated to be 785,800.

Mutant

Mutant

In biology, and especially in genetics, a mutant is an organism or a new genetic character arising or resulting from an instance of mutation, which is generally an alteration of the DNA sequence of the genome or chromosome of an organism. It is a characteristic that would not be observed naturally in a specimen. The term mutant is also applied to a virus with an alteration in its nucleotide sequence whose genome is in the nuclear genome. The natural occurrence of genetic mutations is integral to the process of evolution. The study of mutants is an integral part of biology; by understanding the effect that a mutation in a gene has, it is possible to establish the normal function of that gene.

Lineage (evolution)

Lineage (evolution)

An evolutionary lineage is a temporal series of populations, organisms, cells, or genes connected by a continuous line of descent from ancestor to descendant. Lineages are subsets of the evolutionary tree of life. Lineages are often determined by the techniques of molecular systematics.

Ohio State University

Ohio State University

The Ohio State University, commonly called Ohio State or OSU, is a public land-grant research university in Columbus, Ohio. A member of the University System of Ohio, Ohio State was founded in 1870 as the state's land-grant university and the ninth university in Ohio with the Morrill Act of 1862. Ohio State was originally known as the Ohio Agricultural and Mechanical College and focused on various agricultural and mechanical disciplines, but it developed into a comprehensive university under the direction of then-Governor and later U.S. president Rutherford B. Hayes, and in 1878, the Ohio General Assembly passed a law changing the name to "the Ohio State University" and broadening the scope of the university. Admission standards tightened and became greatly more selective throughout the 2000s and 2010s.

Europe

Europe

Europe is a continent comprising the westernmost peninsulas of Eurasia, located entirely in the Northern Hemisphere and mostly in the Eastern Hemisphere. It shares the continental landmass of Afro-Eurasia with both Africa and Asia. It is bordered by the Arctic Ocean to the north, the Atlantic Ocean to the west, the Mediterranean Sea to the south, and Asia to the east. Europe is commonly considered to be separated from Asia by the watershed of the Ural Mountains, the Ural River, the Caspian Sea, the Greater Caucasus, the Black Sea and the waterways of the Turkish Straits.

Institut national de la recherche agronomique

Institut national de la recherche agronomique

The Institut national de la recherche agronomique was a French public research institute dedicated to agricultural science. It was founded in 1946 and is a Public Scientific and Technical Research Establishment under the joint authority of the Ministries of Research and Agriculture. From 1 January 2020 the INRA merged with the IRSTEA to create the INRAE.

Source: "Nottingham Arabidopsis Stock Centre", Wikipedia, Wikimedia Foundation, (2022, October 21st), https://en.wikipedia.org/wiki/Nottingham_Arabidopsis_Stock_Centre.

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Further Reading

Arabidopsis

Arabidopsis thaliana

Vernalization

Abscisic acid

Transfer DNA

Hydrotropism

ABC model of flower development

Caroline Dean

Plant genetics
References
  1. ^ David Meinke and Randy Scholl. (November 2003). "The Preservation of Plant Genetic Resources. Experiences with Arabidopsis" (PDF). Plant Physiology. 133 (3): 1046–1050. doi:10.1104/pp.103.024877. PMC 523880. PMID 14612584.
  2. ^ Maarten Koornneef and David Meinke (March 2010). "The development of Arabidopsis as a model plant". Plant Journal. 61 (3): 909–21. doi:10.1111/j.1365-313X.2009.04086.x. PMID 20409266.
  3. ^ "Archived copy" (PDF). Archived from the original (PDF) on 23 May 2010. Retrieved 24 April 2014.{{cite web}}: CS1 maint: archived copy as title (link)
  4. ^ Kleinboelting; et al. (2012). "GABI-Kat SimpleSearch: new features of the Arabidopsis thaliana T-DNA mutant database". Nucleic Acids Research. 40 (Database issue): D1211–5. doi:10.1093/nar/gkr1047. PMC 3245140. PMID 22080561.
  5. ^ Alonso; et al. (2003). "Genome-Wide Insertional Mutagenesis of Arabidopsis thaliana". Science. 301 (5633): 653–657. Bibcode:2003Sci...301..653A. doi:10.1126/science.1086391. PMID 12893945. S2CID 30755818.
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